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Cell Applications Inc
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ATCC
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ScienCell
hpaecs Hpaecs, supplied by ScienCell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/human+primary+paecs+(hpaecs)+from+the+pulmonary+artery+tissue/hpaecs/pmc06579982-34-0-6 Average 90 stars, based on 1 article reviews
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ScienCell
primary human paecs (hpaecs) ![]() Primary Human Paecs (Hpaecs), supplied by ScienCell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/human+primary+paecs+(hpaecs)+from+the+pulmonary+artery+tissue/human+paecs/pmc07797426-77-0-11 Average 90 stars, based on 1 article reviews
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ScienCell
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promocell
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ScienCell
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Qiagen
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ScienCell
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ScienCell
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MitoQ Ltd
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Image Search Results
Journal: International Journal of Molecular Medicine
Article Title: Astragaloside IV blocks monocrotaline-induced pulmonary arterial hypertension by improving inflammation and pulmonary artery remodeling
doi: 10.3892/ijmm.2020.4813
Figure Lengend Snippet: ASIV attenuates hypoxia-induced HPAEC dysfunction. (A) TNF-α concentration in HPAEC culture media. (B) IL-1β concentration in HPAEC culture media. (C) Western blot analysis of HIF-1α and VEGF protein levels in HPAECs under normoxic or hypoxic conditions. (D) HIF-1α and VEGF protein levels, respectively (relative to normoxia group). Values are the means ± SEM of 3 independent experiments. * P<0.01 compared with the normoxia group; # P<0.05; ## P<0.01, compared with the hypoxia group. ASIV, astragaloside IV; HPAEC, human pulmonary artery endothelial cell; N, normoxia; H, hypoxia.
Article Snippet:
Techniques: Concentration Assay, Western Blot
Journal: International Journal of Molecular Medicine
Article Title: Astragaloside IV blocks monocrotaline-induced pulmonary arterial hypertension by improving inflammation and pulmonary artery remodeling
doi: 10.3892/ijmm.2020.4813
Figure Lengend Snippet: ASIV decreases HIF-1α and p-ERK1/2 protein levels, and increases p27 and p21 protein levels in HPASMCs. (A and B) Western blot analysis of HIF-1α, p-ERK1/2, p27 and p21 protein levels in HPASMCs under normoxic or hypoxic conditions. (C-E) HIF-1α, p-ERK1/2, p27 and p21 protein levels, respectively (relative to normoxia group). Values are means ± SEM of 3 independent experiments. * P<0.01 compared with the normoxia group; ## P<0.01, compared with the hypoxia group. ASIV, astragaloside IV; HPASMCs, human pulmonary artery smooth muscle cells; N, normoxia; H, hypoxia.
Article Snippet: Primary human PAECs (HPAECs) and
Techniques: Western Blot
Journal: International Journal of Molecular Medicine
Article Title: Astragaloside IV blocks monocrotaline-induced pulmonary arterial hypertension by improving inflammation and pulmonary artery remodeling
doi: 10.3892/ijmm.2020.4813
Figure Lengend Snippet: ASIV promotes HPASMC apoptosis. (A) Representative images of TUNEL-positive HPASMCs treated with various concentrations of ASIV under normoxic or hypoxic conditions. Cells undergoing apoptosis were positively stained with TUNEL reagent and are shown in green (scale bar, 100 µ m). (B) TUNEL-positive HPASMC expression (relative to normoxia group). (C and D) Western blot analysis of Bcl-2, Bax, cleaved caspase-3 and cleaved caspase-9 protein levels in HPASMCs under normoxic or hypoxic conditions. (E) Ratio of Bcl-2/Bax (relative to normoxic group). (F) Cleaved caspase-3 and cleaved caspase-9 protein levels, respectively (relative to normoxic group). Values are the means ± SEM of 3 independent experiments. * P<0.01 compared with the normoxia group; ## P<0.01, compared with the hypoxia group. ASIV, astragaloside IV; HPASMCs, human pulmonary artery smooth muscle cells; N, normoxia; H, hypoxia.
Article Snippet: Primary human PAECs (HPAECs) and
Techniques: TUNEL Assay, Staining, Expressing, Western Blot